Himself / Host / Presenter / Cool Cat
Derek Savage
Himself / Co-Presenter / Scientist Sam / Blunt Boy / "Keanu Reeves" / "Taylor Swift" / "John Travolta" / "Lil Nas X" / "Tara Reid"
Alistair Cooper
Himself / Various (archive footage)
John Travolta
Himself / Various (archive footage)
Dave Franco
Himself / Various (archive footage)
Eddie Murphy
Himself / Bustopher Jones / Various (archive footage)
James Corden
Himself / Various (archive footage)
Zac Efron
Herself (archive footage)
Margot Robbie
Herself (archive footage)
Lily James
Herself (archive footage)
Zendaya
Herself (archive footage)
Hailee Steinfeld
Herself (archive footage)
Scarlett Johansson
Himself (archive footage)
Harry Styles
Himself (archive footage)
Post Malone
Himself (archive footage)
Lil Nas X
Himself (archive footage)
Ed Sheeran
Himself (archive footage)
Bruno Mars
Herself (archive footage)
Lana Del Rey
Herself (archive footage)
Halsey
Herself (archive footage)
Lizzo
Herself (archive footage)
Billie Eilish
Herself (archive footage)
Ariana Grande
Dio Brando (archive footage)
Patrick Seitz
Jonathan Joestar (archive footage)
Johnny Yong Bosch